What you may be feelingPeople with myeloproliferative neoplasms (MPNs) can find themselves coping with many stressors. For some patients, MPNs are chronic illnesses which can be life-threatening. If you are diagnosed with an MPN you may feel low in mood or fluctuate into and out of depression. The impact of loss Whilst some patients face less difficult situations, others find themselves coping with a huge and increasing set of potential losses; loss of autonomy, loss of physical control, emotional loss. Simply living with the threat of premature death can be a major source of anxiety for some patients. This threat can at times cause people to behave in strange and irrational ways. Stresses you may feel If you have an MPN, you may experience a variety of stressors, including: Uncertainty about the future Difficult treatment options Unpleasant symptoms Medication side effects Loss of control Changes in self image Potentially difficult pregnancies Possible inability to have children Problems maintaining relationships Threat to life Changes over time You may find that at certain times in your life you may feel less able to cope with this chronic illness. This can happen if you need to change your treatment plan, if you find that your condition is becoming worse, or if you are going through other events and transitions in your life. What you can do These are normal feelings for anyone with a chronic illness. You may find it helpful to talk with a friend or an MPN buddy, to talk with a psychologist, or to write down your feelings in a journal. Contact us at firstname.lastname@example.org if you need more information.