The vlogcast features Dr Patrick Harrington, Consultant Haematologist, Guy’s & St Thomas’ Hospital, discussing the new study on thrombosis risk in MPN patients using QRISK3 Score. Dr Harrington explains the research the team at Guy’s Hospital have done to see if a new way of assessing patients’ risk of thrombosis (clotting) called QRISK3, could be a useful tool for patients and their clinicians to judge their risk of having a clot. The research shows that QRISK3 is an accurate way of assessing risk and is likely to lead to it being used by MPN clinicians from now on.
The Study:
- Used the QRISK3 score, a tool developed to estimate a person’s 10-year risk of heart attack or stroke, factoring in age, ethnicity, location, and various health metrics
- Analyzed data from >10,000 ET and PV patients treated at Guy’s & St Thomas’ Hospital
- Patients had a median 8-year follow-up. You can read the study publication here…
Practical Implications for Patients:
- Patients can calculate their QRISK3 score online https://www.qrisk.org
- If the score is elevated, it’s worth discussing modifying risk factors (like BMI, cholesterol, blood pressure) with a GP
- Patients with high scores but no current cytoreductive therapy should talk to their haematologist, especially those around “borderline” age (50s–60s)
Next Steps:
- The team hopes to expand the study across more centres and internationally to validate findings beyond a single hospital
We hope that you enjoyed this conversation, please send feedback and any questions to info@mpnvoice.org.uk. If you have any suggestions for future conversations please let us know.
We would like to thank Dr Harrington for taking part in this conversation with Nona.
Donate to MPN Voice – MPN Voice would not exist without donations, fundraising and grants, we are kindly asking everyone to be as generous as they can to help us support our ongoing projects supporting the MPN patient and healthcare communities. We would be very grateful for your support with a donation to MPN Voice which you can make via the MPN Voice JustGiving page, thank you.
